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cobicistat will increase the stage or outcome of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Carefully. A diminished dose of diazepam may be requiredLonafarnib could improve the AUC and peak concentration of CYP2C19 substrates. If coadministration unavoidable, monitor for adverse reactions and les

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